Florence County Vacations & Trips from $648
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Your Florence County Vacation
Leave the planning up to us with a Florence County vacation package. With everything arranged before you leave home, the only thing left to do is sit back, chill out and enjoy this destination's countless delights. A trip to Florence County wouldn't be complete without getting to some of its best cities, starting with Florence. Two of the most popular attractions here include Magnolia Mall and Mcleod Regional Medical Center. Lake City is another favorite city with Florence County travelers. Visitors to this exciting destination enjoy The Country Club at Lake City and Moore Farms Botanical Garden. Expedia is a one-stop shop for planning your Florence County vacation. From flights and accommodations, to rental cars and activities, we know how to create a travel experience like no other.
Top destinations in Florence County
Lake City
The Latest Florence County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Westgate Myrtle Beach Oceanfront Resort
Save 100% on your flight
Price was $1,059, price is now $648 per person
$648
per person
Aug 14 - Aug 17
found 1 day ago
Roundtrip flight included
Boston (BOS) to Myrtle Beach (MYR)
8.6/10 Excellent! (1,209 reviews)
The facility was great, employees were very nice, woll be staying again.
Reviewed on Jun 26, 2026
Marina Inn At Grande Dunes
Save 100% on your flight
Price was $2,207, price is now $1,478 per person
$1,478
per person
Aug 9 - Aug 16
found 1 day ago
Roundtrip flight included
Boston (BOS) to Myrtle Beach (MYR)
9.4/10 Exceptional! (1,766 reviews)
The hotel itself was perfect for our stay. The valets were great to get information from. Some of the other staff were not helpful or crabby. Our flight didn't leave until the evening so we asked for a late check-out option. They stated that the indoor pool had showers and bathrooms to get ready in. I wish I would've checked it out before assuming it would work for us. We spent the day at the pool and beach. When it was time to get ready for the airport we went to the indoor pool. There were no showers. The shower that was there was a rinse off shower out by the pool. I was very disappointed!
Reviewed on Jun 29, 2026
North Beach Resort & Villas
Windy Hill
Save 100% on your flight
Price was $2,027, price is now $1,387 per person
$1,387
per person
Aug 9 - Aug 16
found 1 day ago
Roundtrip flight included
Boston (BOS) to Myrtle Beach (MYR)
8.8/10 Excellent! (1,004 reviews)
Loved the home we stayed in. Clean. Spacious. Easy to travel to and from. Well maintained. Short distance to many food options, activities, etc.
Reviewed on Jun 29, 2026
Marina Inn Grande Dunes Condos & Suites
Save 100% on your flight
Price was $2,284, price is now $1,584 per person
$1,584
per person
Aug 9 - Aug 16
found 1 day ago
Roundtrip flight included
Boston (BOS) to Myrtle Beach (MYR)
9.4/10 Exceptional! (150 reviews)
I like this location as I’ve stayed here before. Bathrooms were pretty nasty with trash and hair everywhere. Not sure they mopped or cleaned the toilets before we checked in. There was also hair in the fridge? No dish soap or paper towels which was a little disappointing considering it has a full kitchen with dishwasher. Rooms could definitely use some new carpet as they were gross with stains everywhere. Living room chair was cut with big hole. Beds were fairly comfortable. Nice view of waterway and golf course.
Reviewed on Jun 28, 2026
Ocean Isle Inn
Save 100% on your flight
Price was $979, price is now $680 per person
$680
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip flight included
Islip (ISP) to Myrtle Beach (MYR)
9.4/10 Exceptional! (1,001 reviews)
Amazing hotel right on the beach! Clean and friendly staff. Walking distance from restaurants. Great stay!
Reviewed on Jun 24, 2026
Find the Best Florence County Vacation Packages
Florence County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Florence Regional Airport (FLO) |
Top Sights | Palmetto Shores Lake, Columns Plantation and Florence Veterans Park |
Florence County Hotel Deals
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Jul 5 to Jul 6
$100 total
Jul 5 - Jul 6
Total with taxes and fees
9/10 Wonderful! (2,322 reviews)
"Nice place to stay well worth it"
Reviewed on Jun 28, 2026
Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jul 5 to Jul 6
$79 total
Jul 5 - Jul 6
Total with taxes and fees
8.6/10 Excellent! (2,688 reviews)
"You get what you pay for. Does the job. Would stay again while driving 95 and need a place to crash for the night."
Reviewed on Jun 29, 2026
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundable
$114 nightly
The price is $127 total per night from Jul 7 to Jul 8
$127 total
Jul 7 - Jul 8
Total with taxes and fees
9/10 Wonderful! (1,310 reviews)
"Great place to stay. Quiet. Great location. Janice at the front desk was so sweet and very helpful. She is an asset to the staff there for sure."
Reviewed on Jun 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
