Florence County Vacations & Trips from $648
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Your Florence County Vacation
Leave the planning up to us with a Florence County vacation package. With everything arranged before you leave home, the only thing left to do is sit back, chill out and enjoy this destination's countless delights. A trip to Florence County wouldn't be complete without getting to some of its best cities, starting with Florence. Two of the most popular attractions here include Magnolia Mall and Mcleod Regional Medical Center. Lake City is another favorite city with Florence County travelers. Visitors to this exciting destination enjoy The Country Club at Lake City and Moore Farms Botanical Garden. Expedia is a one-stop shop for planning your Florence County vacation. From flights and accommodations, to rental cars and activities, we know how to create a travel experience like no other.
Top destinations in Florence County
Lake City
The Latest Florence County Vacation Packages
Price found within the past 48 hours. Click for updated prices.
Westgate Myrtle Beach Oceanfront Resort
Save 100% on your flight
Price was $1,059, price is now $648 per person
$648
per person
Aug 14 - Aug 17
found 1 day ago
Roundtrip flight included
Boston (BOS) to Myrtle Beach (MYR)
8.6/10 Excellent! (1,209 reviews)
An amazing stay!!!! We will be back!!
Reviewed on Jun 29, 2026
Marina Inn At Grande Dunes
Save 100% on your flight
Price was $1,162, price is now $790 per person
$790
per person
Sep 2 - Sep 6
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Myrtle Beach (MYR)
9.4/10 Exceptional! (1,766 reviews)
Beautiful grounds, clean property, friendly staff.
Reviewed on Jun 30, 2026
Ocean Isle Inn
Save 100% on your flight
Price was $964, price is now $660 per person
$660
per person
Sep 17 - Sep 21
found 1 day ago
Roundtrip flight included
Islip (ISP) to Myrtle Beach (MYR)
9.4/10 Exceptional! (1,001 reviews)
Amazing hotel right on the beach! Clean and friendly staff. Walking distance from restaurants. Great stay!
Reviewed on Jun 24, 2026
Ocean Villas Beach Resort
Save 100% on your flight
Price was $1,230, price is now $865 per person
$865
per person
Aug 18 - Aug 24
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Myrtle Beach (MYR)
8.4/10 Very Good! (35 reviews)
I love the stay everything was Awesome!!!!!
Reviewed on Mar 25, 2024
Marina Inn Grande Dunes Condos & Suites
Save 100% on your flight
Price was $1,221, price is now $868 per person
$868
per person
Sep 2 - Sep 6
found 1 day ago
Roundtrip non-stop flight included
Boston (BOS) to Myrtle Beach (MYR)
9.4/10 Exceptional! (150 reviews)
I like this location as I’ve stayed here before. Bathrooms were pretty nasty with trash and hair everywhere. Not sure they mopped or cleaned the toilets before we checked in. There was also hair in the fridge? No dish soap or paper towels which was a little disappointing considering it has a full kitchen with dishwasher. Rooms could definitely use some new carpet as they were gross with stains everywhere. Living room chair was cut with big hole. Beds were fairly comfortable. Nice view of waterway and golf course.
Reviewed on Jun 28, 2026
Find the Best Florence County Vacation Packages
Florence County Essential Information
Language | English |
|---|---|
Currency | U.S dollars |
Closest Airport | Florence Regional Airport (FLO) |
Top Sights | Palmetto Shores Lake, Columns Plantation and Florence Veterans Park |
Florence County Hotel Deals
Park Inn by Radisson Florence, SC
1729 Mandeville Road Florence SC
Fully refundable
$89 nightly
The price is $100 total per night from Jul 5 to Jul 6
$100 total
Jul 5 - Jul 6
Total with taxes and fees
9/10 Wonderful! (2,322 reviews)
"Nice place to stay well worth it"
Reviewed on Jun 28, 2026
Howard Johnson by Wyndham Florence
2038 W Lucas Street Florence SC
Fully refundableReserve now, pay when you stay
$70 nightly
The price is $79 total per night from Jul 5 to Jul 6
$79 total
Jul 5 - Jul 6
Total with taxes and fees
8.6/10 Excellent! (2,671 reviews)
"The breakfast was nothing to write home about. There was black spots on our bed that when we went to wipe it off it smeared. The TV did work. We were only there for like 9 hours but I had reserved a room again for in a week and I canceled that reservation to stay somewhere else for just $45 more ..."
Reviewed on Jun 30, 2026
Comfort Inn & Suites Florence Center Area
527 Woody Jones Blvd Florence SC
Fully refundable
$114 nightly
The price is $127 total per night from Jul 7 to Jul 8
$127 total
Jul 7 - Jul 8
Total with taxes and fees
9/10 Wonderful! (1,310 reviews)
"Great place to stay. Quiet. Great location. Janice at the front desk was so sweet and very helpful. She is an asset to the staff there for sure."
Reviewed on Jun 30, 2026
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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* Savings based on package bookings compared to the price of the same components booked separately. Savings not available on all packages.
